Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of tyrosine hydroxylase in rat tissue homogenates, cell lysates, cell culture supernates.
Target Information: The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]